Thelansis

  Gastroesophageal junction adenocarcinoma is a type of carcinoma in which the tumor's epicenter is located within the GEJ region. It is a significant clinical problem that increases disease burden and poor prognosis. Most patients present with advanced disease, and less than half receive curative treatment. In most studies, tumor infiltration of the proximal or distal resection margin has been linked to a lower chance of survival. The Siewert classification is used for adenocarcinomas located within 5 cm of the GEJ. The three types of GEJ adenocarcinomas are as follows. Type I adenocarcinoma of the distal esophagus is found 1–5 cm above the GEJ. Type II is a true cardia carcinoma located between 1 cm above and 2 cm below the GEJ. Subcardial carcinoma of type III is found 2–5 cm below the GEJ. Adenocarcinoma of the gastroesophageal junction (GEJ) is a significant clinical problem with an increasing incidence and a poor prognosis. Most patients present with advanced disease, and l...