Thelansis

 Neurofibromatosis 1 (NF1) is a genetic disorder that causes the development of noncancerous nerve and skin tumors, along with areas of unusual skin pigmentation. These pigmented areas typically manifest as pale tan or light brown discolorations and freckles in unexpected locations like underarms or the groin. Penetrance is nearly 100% by age 20, meaning that if a person carries the mutation, they will show symptoms. However, the severity of these symptoms can vary significantly, even among family members with the same mutation. ·        NF1 affects males and females equally, with no significant differences between races or ethnic groups, occurring in approximately 1 in 2,500 to 3,000 births. Inheritability is around 50%, and only one parent with NF1 can pass it on to their child. Thelansis’s “Cutaneous Neurofibromatosis Type 1 Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, e...

 Neurofibromatosis 1 (NF1) is a genetic disorder characterized by the development of multiple noncancerous tumors of nerves and skin and areas of abnormal skin color. Areas of abnormal skin pigmentation typically include pale tan or light brown discolorations and freckling in atypical locations such as under the arms or in the groin. Penetrance approaches 100% by age 20; if the patient has the mutation, they will exhibit manifestations, although expressivity is highly variable, even among family members with the same mutation. ·        It affects males and females both in equal numbers. NF1 affects all races and ethnic groups equally and is estimated to occur in 1 in 2,500 to 3,000 births. ·        The disorder is inherited from a parent in about 50% of individuals with NF1. Only one parent need to be affected to cause a child to have NF1. Thelansis’s “Cutaneous Neurofibromatosis Type 1 Market Outlook, Epidemiology, ...