Thelansis

  Factor VII (F VII) deficiency is the commonest of the ‘rare inherited bleeding disorders characterized by a deficiency or reduced activity of clotting factor VII. It is the complex formed by activated factor VII and tissue factor (TF) which plays a leading role in initiating the extrinsic arm of the coagulation cascade. Individuals with factor VII deficiency can experience prolonged, uncontrolled bleeding episodes. The symptoms and severity of factor VII deficiency are highly variable; no consistent correlation between the amount of factor VII in the blood and overall severity is seen. Some individuals may not develop any symptoms (asymptomatic), including individuals with relatively low levels of factor VII.   ·        The incidence cases of Factor VII (F VII) deficiency ranges between 1.5 to 2.75 cases per 150,000 to 250,000 individuals in the USA.     The competitive landscape of Factor VII Deficiency includes country-spec...