Thelansis

 Malignant mesothelioma is a rare form of cancer arising from the mesothelial cells that line various viscera. It is primarily associated with asbestos exposure and is observed in the pleural lining (malignant pleural mesothelioma). The exact mechanisms by which asbestos exposure leads to the development of malignant mesothelioma are not fully understood but are believed to involve repeated pleural inflammation, interference with cell division, activation of proto-oncogenes, and oxidative stress. The three histological subtypes of mesothelioma are epithelioid, sarcomatoid, and mixed, with the epithelioid subtype associated with a better prognosis. Malignant pleural mesothelioma spreads locally, initially affecting the parietal pleura and then spreading to the visceral pleura, chest wall, diaphragm, or mediastinum. Direct invasion of regional lymph nodes, particularly the bronchopulmonary or hilar nodes, is also observed. The initial symptoms of malignant pleural mesothelioma are us...