Thelansis

  Hypoventilation arises when the alveolar ventilation rate fails to adequately match the body's metabolic carbon dioxide (CO2) production, leading to an elevation in the partial pressure of CO2 (PaCO2) in arterial blood. Enhanced clinical vigilance and monitoring are essential for patients with conditions predisposing them to hypoventilation during sleep. Continuous overnight oximetry is a valuable screening tool to detect early signs of nocturnal desaturation. Theoretically, respiratory stimulants can heighten respiratory drive and ameliorate daytime hypercapnia. Medroxyprogesterone functions as a respiratory stimulant at the hypothalamic level. Domiciliary ventilation has been a longstanding strategy for reversing respiratory failure and extending survival in individuals with severe chronic alveolar hypoventilation. Diagnosis of CRC is established once other prevalent causes of chronic cough have been ruled out or treated, and the cough remains unresponsive...