Thelansis

  Acral lentiginous melanoma (ALM), a rare form of skin cancer, occurs equally across all ethnicities and carries a poorer prognosis compared to other melanoma types. It typically manifests as dark, irregular patches, bumps, or lumps on the feet and less frequently on the hands. Histologically, acral lentiginous melanoma presents with an asymmetrical, poorly defined proliferation of individual melanocytes along the junction between the dermis and epidermis, with single melanocytes being more prevalent than clusters. Differential diagnosis from benign acral lentiginous nevi, which may exhibit localized abnormalities, is crucial. Surgical management is challenging due to the intricate nature and functional importance of the affected extremities, often necessitating reconstructive procedures post-resection. Prognosis depends on the disease stage, generally proving worse compared to other melanoma subtypes, often diagnosed in the sixth or seventh decade of life. Clinically,...