Thelansis

  Primary lateral sclerosis (PLS) is a rare and poorly understood motor neuron disease characterized by progressive dysfunction of the upper motor neurons, resulting in spasticity, mild weakness in voluntary muscle movements, hyperreflexia, and difficulty with motor speech production. The exact cause of PLS remains unknown, and it comprises less than 4% of all cases of motor neuron disease. The clinical presentation of PLS can vary, but it typically begins with progressive spasticity in the legs and later spreads to the arms and bulbar regions and weight loss. Mild frontal lobe dysfunction, memory deficits, and episodes of involuntary emotional expression also characterize PLS. Currently, there is no cure for PLS, and treatment is focused on managing symptoms with medications, assistive devices, and rehabilitation therapy. Optimal care for PLS requires a multidisciplinary team approach. Primary lateral sclerosis incidence in the USA is estimated to be 3.8 per 100,000. ...

 Primary lateral sclerosis (PLS) is a rare and poorly understood motor neuron disease characterized by progressive dysfunction of the upper motor neurons, resulting in spasticity, mild weakness in voluntary muscle movements, hyperreflexia, and difficulty with motor speech production. The exact cause of PLS remains unknown, and it comprises less than 4% of all cases of motor neuron disease. The clinical presentation of PLS can vary, but it typically begins with progressive spasticity in the legs and later spreads to the arms and bulbar regions and weight loss. Mild frontal lobe dysfunction, memory deficits, and episodes of involuntary emotional expression also characterize PLS. Currently, there is no cure for PLS, and treatment is focused on managing symptoms with medications, assistive devices, and rehabilitation therapy. Optimal care for PLS requires a multidisciplinary team approach. ·        Primary lateral sclerosis incidence in the USA is estima...