Thelansis

  Atherosclerosis, a chronic inflammatory condition marked by plaque buildup in arteries, is a leading cause of atherosclerotic cardiovascular disease (ASCVD). These plaques, predominantly lipid-based, trigger inflammation, disrupting blood flow. ASCVD results from various factors, including high LDL cholesterol, hypertension, diabetes, smoking, age (typically over 45 for males, 55 for females), gender (male), and family history of cardiovascular disease. The progression of atherosclerosis primarily involves the continual formation of arterial wall lesions due to lipid retention within the intima, facilitated by substances like proteoglycans. This process exacerbates chronic inflammation at vulnerable arterial sites, significantly affecting atherogenic progression at all stages. Angiography is the main method for imaging atherosclerotic lesions in the coronary circulation, providing crucial insights into coronary morphology. Statins, or HMG-CoA reductase inhib...