Thelansis

 Juvenile myasthenia gravis (JMG) is a rare autoimmune disorder affecting the neuromuscular junction, leading to either ocular manifestations or generalized weakness in individuals under the age of 18. The onset of this condition can occur either before the age of 12 (prepubertal) or after the age of 12 (postpubertal). The primary characteristic of MG is muscle weakness that worsens with exertion. The initial presentation of the disease may be acute or subacute, typically following a chronic course with periods of remission and relapses. In prepubertal children, the ocular presentation is more common and is characterized by fatigable ptosis (drooping of the eyelids), ophthalmoplegia (eye muscle weakness), and diplopia (double vision). On the other hand, postpubertal patients tend to develop generalized weakness more frequently. In the prepubertal group, approximately half of the cases manifest solely as ocular symptoms, which is higher than adult MG cases. In generalized cases, add...