Thelansis

  Cardiotoxicity is a comprehensive term that covers a wide range of effects on the heart, including detectable structural alterations without symptoms, leading to arrhythmias, increased cardiac biomarkers due to stress and heart injury, and both systolic and diastolic dysfunction in the left ventricle, even without signs of heart failure. Cardiotoxicity is a well-recognized complication of fluoropyrimidines, namely 5-fluorouracil and its oral prodrug capecitabine. The risk of this adverse effect is heightened in patients undergoing thoracic radiation therapy simultaneously with multiagent chemotherapy, particularly if there's preexisting cardiac disease. The incidence of cardiotoxicity can be as high as 18% among individuals exposed to fluoropyrimidines. Cardiac toxicity can present in two forms, reversible or irreversible. Reversibility denotes the ability to regain cellular or organ function. However, certain myocardial changes, such as loss of myocardial cells through necrosi...

 Cardiotoxicity is a comprehensive term that covers a wide range of effects on the heart, including detectable structural alterations without symptoms, leading to arrhythmias, increased cardiac biomarkers due to stress and heart injury, and both systolic and diastolic dysfunction in the left ventricle, even without signs of heart failure. Cardiotoxicity is a well-recognized complication of fluoropyrimidines, namely 5-fluorouracil and its oral prodrug capecitabine. The risk of this adverse effect is heightened in patients undergoing thoracic radiation therapy simultaneously with multiagent chemotherapy, particularly if there's preexisting cardiac disease. The incidence of cardiotoxicity can be as high as 18% among individuals exposed to fluoropyrimidines. Cardiac toxicity can present in two forms, reversible or irreversible. Reversibility denotes the ability to regain cellular or organ function. However, certain myocardial changes, such as loss of myocardial cells through necrosis o...