Thelansis

 Neuropathic Ocular Pain (NOP) is caused by a direct injury or functional disturbance of the neural elements involved in detecting and processing nociceptive stimuli. These elements include the peripheral nerve terminals and axons of the nociceptive sensory neurons located in the dorsal root and cephalic sensory ganglia; they also comprise the higher-order neurons of the spinal cord, brain stem, thalamus, and various other subcortical and cortical structures in charge of receiving and processing the peripheral nociceptive input. The abnormal, unpleasant sensation caused by the disturbed functioning of any of the components of the brain pain matrix is called ‘neuropathic pain’ and is typically evoked at the periphery by sensory nerve traumatisms, metabolic diseases such as diabetes, and by the action of a large variety of chemical, toxic, or infectious agents causing damage to peripheral sensory neurons at any point of their trajectory (peripheral neuropathic pain); within the centr...