Thelansis

Immunoglobulin A Nephropathy, called IgAN for short, or Berger’s disease, that occurs when IgA deposits build up in the kidneys and that damages the glomeruli and can cause kidney disease. Etiology- IgA nephropathy is an autoimmune kidney disease. IgA nephropathy have an increased blood level of IgA that contains less of a special sugar, galactose, than normal. This galactose-deficient IgA is considered “foreign” by other antibodies circulating in the blood. As a result, these other antibodies attach to the galactose-deficient IgA and form a clump. This clump is also called an immune complex. Epidemiology- About 1 in every 4 adults with IgA nephropathy eventually gets kidney failure/ESRD. One in every 10 to 20 children will get kidney failure/ESRD because of IgA nephropathy.   The competitive landscape of IgA Nephropathy includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are being tracked ...