Thelansis

 Becker muscular dystrophy (BMD) is an X-linked recessive allelic muscular dystrophy caused by mutations in the DMD gene. BMD is characterised by less severe clinical phenotypes than DMD, with onset mostly during school age, between 5-15 years old, even though there are several reported cases of late-onset BMD in the third and fourth decades of life. BMD clinical phenotypes are varied, ranging from mild symptoms, such as muscle cramps, myalgia, myoglobinuria and mild myopathy, to severe myopathy that can interfere with patient's ability to walk. Cardiac involvement has been reported in 70% of BMD cases. The most common type of cardiac abnormality is dilated cardiomyopathy, which is associated with congestive heart failure and premature death. ·        The incidence of Becker muscular dystrophy (BMD) has been estimated to be between 1 in 18,000 and 1 in 30,000 male births. ·        The prevalence of BMD is estimated to ...

  Becker muscular dystrophy (BMD) is an X-linked recessive allelic muscular dystrophy caused by mutations in the DMD gene. BMD is characterised by less severe clinical phenotypes than DMD, with onset mostly during school age, between 5-15 years old, even though there are several reported cases of late-onset BMD in the third and fourth decades of life. BMD clinical phenotypes are varied, ranging from mild symptoms, such as muscle cramps, myalgia, myoglobinuria and mild myopathy, to severe myopathy that can interfere with patient's ability to walk. Cardiac involvement has been reported in 70% of BMD cases. The most common type of cardiac abnormality is dilated cardiomyopathy, which is associated with congestive heart failure and premature death. The incidence of Becker muscular dystrophy (BMD) has been estimated to be between 1 in 18,000 and 1 in 30,000 male births. The prevalence of BMD is estimated to be 17 to 27 cases per million people. Female carriers of X-lin...