Thelansis

 Neurofibromatosis type 1 (NF1) is a neurocutaneous genetic disorder known for its diverse clinical manifestations, including café-au-lait spots, Lisch nodules in the iris, freckling in axillary and inguinal regions, and multiple neurofibromas. NF1 condition exhibits significant variability in clinical features, even among individuals within the same family. Almost all patients display multiple café-au-lait macules, some present at birth and most emerging within the first year of life. Intertriginous freckling typically begins around the age of 5. In adults, cutaneous and subcutaneous neurofibromas develop and continue to increase in number and size with age. It's important to note that these cutaneous neurofibromas do not turn malignant. However, plexiform neurofibromas, which grow along nerves and their branches, may cause disfigurement, pain, and functional impairments. They are usually present at birth and may become malignant later in life. Ocular manifestations of NF1 include...

  Uterine Neurofibromatosis type 1 (NF1) is a neurocutaneous genetic disorder known for its diverse clinical manifestations, including café-au-lait spots, Lisch nodules in the iris, freckling in axillary and inguinal regions, and multiple neurofibromas. NF1 condition exhibits significant variability in clinical features, even among individuals within the same family. Almost all patients display multiple café-au-lait macules, some present at birth and most emerging within the first year of life. Intertriginous freckling typically begins around the age of 5. In adults, cutaneous and subcutaneous neurofibromas develop and continue to increase in number and size with age. It's important to note that these cutaneous neurofibromas do not turn malignant. However, plexiform neurofibromas, which grow along nerves and their branches, may cause disfigurement, pain, and functional impairments. They are usually present at birth and may become malignant later in life. Ocular manifestations of...