Thelansis

  Evolution of I/O targeted therapies and expectations of cancer patients and physicians Over the past five years, antibodies have become the best-selling drugs in the pharmaceutical market; eight of the top ten bestselling drugs worldwide were biologics. The global therapeutic monoclonal antibody market is expected to generate revenue of $300 billion by 2025.   Immunotherapy is a promising cancer therapy where the immune system is manipulated to attack cancer cells. It has hinted at better patient survival and quality of life compared to the other methods. The effectiveness of immunotherapy has been known from as early as the 19th century when, William Coley, MD used a concoction of inactivated bacteria (popularly known as Coley’s toxin) to infect the tumor area resulting in remission of the tumor. Yet, there was insufficient understanding of the mechanism. It was nearly half a century later that concepts of immune system response shed light on the potential of cancer immunother