Marginal Zone Lymphoma (MZL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Marginal zone lymphoma (MZL), the second most common indolent non-Hodgkin's lymphoma (iNHL) and the third in overall prevalence among B-cell non-Hodgkin's lymphomas (NHL) account for approximately 8% to 12% of cases. MZL comprises three primary subtypes: extranodal MZL (EMZL) originating in mucosa-associated lymphoid tissue (MALT or gastric GALT), splenic MZL, and nodal MZL. At the time of diagnosis, most splenic MZL (SMZL) patients are typically asymptomatic, with incidental findings of anemia, thrombocytopenia, or lymphocytosis through routine blood tests. The development of MZL is predominantly linked to chronic antigen-induced activation of the B-cell receptor (BCR). · The age-standardized incidence rate for MZL in the United States is 27.6 cases per million, with a slightly higher prevalence in males (19.1 cases) than females. EMZL constitutes most MZL cases, accounting for 60.8%, followed by nodal MZL (30.3%) and SMZL (8.9%). ...