Thelansis

 Hypertrophic cardiomyopathy (HCM) is a genetic disorder affecting cardiac myocytes, characterized by cardiac hypertrophy, which loading conditions cannot explain, a nondilated left ventricle, and a normal or increased or increased ejection fraction. Cardiac hypertrophy is typically asymmetric and commonly involves the basal interventricular septum subjacent to the aortic valve, although other myocardial regions may also be affected. At the cellular level, cardiac myocytes are hypertrophied, disorganized, and separated by areas of interstitial fibrosis. Most patients with HCM are asymptomatic or have minimal symptoms. However, the condition can cause a range of pathophysiological features, including diastolic ventricular dysfunction, obstruction to the left ventricular outflow tract, an imbalance between myocardial oxygen supply and demand, and cardiac arrhythmias. Patients with HCM may exhibit a variable phenotype, with ventricular hypertrophy being the cardinal manifestation and myoc