Thelansis

 Iron Overload indicates a physical condition resulting in increased total body iron stores, with or without organ dysfunction. In other words, it refers to a cluster of genetic or acquired conditions that result in the extra accumulation of iron in the body. Since excess iron is toxic to the cells, its collection can lead to permanent tissue damage, resulting in organ failure if left untreated for a prolonged period. Iron Overload is caused by an inherited disorder called hereditary hemochromatosis (HH) or is acquired in patients with certain conditions that need frequent blood transfusions. Iron homeostasis depends on a complex feedback mechanism between body iron requirements and intestinal absorption. Humans lack a physiological mechanism for the excretion of excess iron. The hormone hepcidin, a 25-amino acid peptide, is produced mainly in the liver and secreted into the blood and is now recognized as the critical regulator of iron homeostasis. Any disruptions in the regulation...

  Iron Overload indicates a physical condition resulting in increased total body iron stores, with or without organ dysfunction. In other words, it refers to a cluster of genetic or acquired conditions that result in the extra accumulation of iron in the body. Since excess iron is toxic to the cells, its collection can lead to permanent tissue damage, resulting in organ failure if left untreated for a prolonged period. Iron Overload is caused by an inherited disorder called hereditary hemochromatosis (HH) or is acquired in patients with certain conditions that need frequent blood transfusions. Iron homeostasis depends on a complex feedback mechanism between body iron requirements and intestinal absorption. Humans lack a physiological mechanism for the excretion of excess iron. The hormone hepcidin, a 25-amino acid peptide, is produced mainly in the liver and secreted into the blood and is now recognized as the critical regulator of iron homeostasis. Any disruptions in the regulatio...

  Iron Overload indicates a physical condition resulting in increased total body iron stores, with or without organ dysfunction. In other words, it refers to a cluster of genetic or acquired conditions that result in the extra accumulation of iron in the body. Since excess iron is toxic to the cells, its collection can lead to permanent tissue damage, resulting in organ failure if left untreated for a prolonged period. Iron Overload is caused by an inherited disorder called hereditary hemochromatosis (HH) or is acquired in patients with certain conditions that need frequent blood transfusions. Iron homeostasis depends on a complex feedback mechanism between body iron requirements and intestinal absorption. Humans lack a physiological mechanism for the excretion of excess iron. The hormone hepcidin, a 25-amino acid peptide, is produced mainly in the liver and secreted into the blood and is now recognized as the critical regulator of iron homeostasis. Any disruptions in the regulatio...