Thelansis

  ANCA-Associated Vasculitis (AAV) is a collection of relatively rare autoimmune diseases of unknown cause, characterized by inflammatory cell infiltration causing necrosis of blood vessels. The clinical spectrum of the AAV is broad and hence the presentation can be quite varied, ranging from a skin rash to fulminant multisystem disease. Typical features of GPA include nasal crusting, stuffiness and epistaxis, uveitis, upper respiratory tract involvement, and often, when in the context of active urinary sediment, renal involvement. Patients with MPA are typically older and present with more severe renal disease than GPA together with rash and neuropathy. ·        ANCA-associated vasculitis (AAV) with a worldwide reported annual incidence ranging from 1.7 to 2.89 cases per 100,000 individuals and a prevalence of 12.5 to 19.2 cases per 100,000 individuals. The competitive landscape of ANCA-Associated Vasculitis includes country-specific approved and ...