Thelansis

 Systemic Lupus Erythematosus (SLE) is a multifaceted autoimmune disease with many clinical symptoms, diverse immunological and laboratory irregularities, and variable outcomes. It predominantly affects women, with a male-to-female ratio of about 1:9. Studies reveal a higher incidence and prevalence in women than men, with rates approximately six times higher. In juvenile SLE patients in the Western world, 5-year survival rates now range from 94% to 100%, but the 10-year survival rate remains somewhat lower, at 81% to 92%. However, this rate drops to 65% in Asian patients with renal involvement. Age significantly influences SLE, with its peak incidence typically occurring during the reproductive years. Renal involvement is a common aspect of SLE, affecting 81% of children and 46% of adults. For most patients, it becomes apparent within two years of the disease's onset, and the histological patterns of lupus nephritis in children closely resemble those in adults.   Thelansi...

 Systemic Lupus Erythematosus (SLE) is a multifaceted autoimmune disease with many clinical symptoms, diverse immunological and laboratory irregularities, and variable outcomes. It predominantly affects women, with a male-to-female ratio of about 1:9. Studies reveal a higher incidence and prevalence in women than men, with rates approximately six times higher. In juvenile SLE patients in the Western world, 5-year survival rates now range from 94% to 100%, but the 10-year survival rate remains somewhat lower, at 81% to 92%. However, this rate drops to 65% in Asian patients with renal involvement. Age significantly influences SLE, with its peak incidence typically occurring during the reproductive years. Renal involvement is a common aspect of SLE, affecting 81% of children and 46% of adults. For most patients, it becomes apparent within two years of the disease's onset, and the histological patterns of lupus nephritis in children closely resemble those in adults.   Thelansi...

 Systemic Lupus Erythematosus (SLE) is a complex multisystemic autoimmune disease characterized by a wide spectrum of clinical manifestations, an overabundance of immunological and laboratory abnormalities, and a variable course and outcome. It is widely known that SLE is much more common in women than in men, with a ratio close to 9:1. In the aforementioned Medicaid study, the incidence and prevalence of SLE were six times higher in women (30.5 and 192.2, respectively) than in men (4.9 and 31.8, respectively). The 5-year survival rates in juvenile SLE patients in the Western world are now 94% to 100%; however, the 10-year survival rate remains disappointing at only 81% to 92% in juvenile SLE, with lower rates (65%) in Asian patients with associated renal involvement. ·        Age is one of the major factors affecting the clinical manifestations and prognosis of SLE patients. SLE may develop at any age, although its peak incidence occurs during the r...