Thelansis

 Fibrolamellar Carcinoma (FLC), a rare form of liver cancer typically found in individuals under 40 years old, is distinct from other liver cancers as it occurs in those with healthy livers. Its exact cause remains poorly understood, though recent studies suggest a chromosome 19 deletion resulting in an anomalous fusion of DNAJB1 and PRKACA genes may be pivotal in its development. Patients usually present with a sizable solitary liver mass alongside nonspecific symptoms. Histologically, FLC displays characteristic features such as large polygonal cells with oncocytic cytoplasm, prominent nucleoli, and dense collagen bands separating trabeculae and cords. Differential diagnosis distinguishes it from classical hepatocellular carcinoma and intrahepatic cholangiocarcinoma through immunohistochemical studies, including markers like cytokeratin 7, CD68, and HepPar-1. Furthermore, FLC is distinguished by the activation of protein kinase A. The prognosis for FLC resembles that of classical...

 Fibrolamellar Carcinoma (FLC) is a rare liver cancer that usually grows in teens and adults under 40 years old. This type of cancer differs from other types of liver cancer because it happens in people with healthy livers. The exact underlying cause of fibrolamellar carcinoma (FLC) is poorly understood. Recent research suggests that a deletion on chromosome 19, which leads to the abnormal combination of two genes, the DNAJB1 and the PRKACA genes, may play a key role in the FLC. ·        Fibrolamellar Carcinoma (FLC) affects both men and women and affects approximately 1 in 5,000,000 people in the general population. Thelansis’s “Fibrolamellar Carcinoma (FLC) Market Outlook, Epidemiology, Competitive Landscape , and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, ...