Wet Age-Related Macular Degeneration (AMD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

The most common cause of visual impairment among elderly patients in developed countries is wet age-related macular degeneration (ARMD), which is characterized by the growth of choroidal neovascularization (CNV) driven by vascular endothelial growth factor (VEGF). CNV can result in bleeding under the retina, detachment or atrophy of the retinal pigment epithelium (RPE), or fluid accumulation under the retina or RPE, leading to vision loss. Wet ARMD differs from dry ARMD by the presence of CNV, where new blood vessels from the choroid invade Bruch's membrane and proliferate either between the membrane and RPE or in the subretinal space. The multifactorial nature of wet ARMD includes numerous risk factors such as older age, elevated total serum cholesterol, micronutrient deficiency, smoking, family history, hypertension, cardiovascular disease, and visible light exposure. Genetic predisposition to ARMD is also apparent, with at least 34 genetic loci and 52 gene variants associated w...