Polyarticular Juvenile Idiopathic Arthritis (PJIA) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Polyarticular Juvenile Idiopathic Arthritis (PJIA), a rare form of juvenile idiopathic arthritis, is characterized by the persistence of arthritis that begins before age 16 and affects at least five joints for more than six weeks within the first six months of onset. This subgroup can be divided into two categories: one with a positive rheumatoid factor (RF) test and the other with a negative RF test. The former requires at least two RF positive tests, spaced at least 3 months apart during the initial 6-month period. Both subgroups are more prevalent among girls and may present with mild fever, weight loss, anemia, moderate hepatosplenomegaly, and mild growth retardation. Children diagnosed with polyarticular JIA often face a more challenging disease course than those with fewer affected joints. Their prolonged active disease course increases their risk of joint damage, leading to poorer functional outcomes and reduced quality of life. Key indicators of a poor prognosis for polyarticular JIA, as outlined in the ACR recommendations for JIA, include the presence of positive RF antibodies, positive anti-CCP antibodies, hip arthritis, cervical spine arthritis, and the presence of erosions or joint space narrowing on radiographs. Additional factors linked to an unfavorable prognosis are early hand involvement and radiographic changes in carpal length within the first year of diagnosis. The primary goals of treatment are achieving disease remission, managing pain, and improving overall functioning. Nonsteroidal anti-inflammatory drugs (NSAIDs) remain the most commonly prescribed medication for inflammatory arthritides, including JIA. NSAIDs work by inhibiting cyclooxygenase-1 and cyclooxygenase-2, thereby blocking prostaglandin formation and providing analgesic and anti-inflammatory effects.

Thelansis’s “Polyarticular Juvenile Idiopathic Arthritis (PJIA) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Polyarticular Juvenile Idiopathic Arthritis (PJIA) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Polyarticular Juvenile Idiopathic Arthritis (PJIA) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Polyarticular Juvenile Idiopathic Arthritis (PJIA) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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