Opioid-Induced Constipation (OIC) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Opioid-induced constipation (OIC) is defined as new or worsening of constipation symptoms after initiating, increasing, or modifying opioid therapy and is common in patients on chronic opioid therapy.
Etiology-
OIC is
primarily mediated through the effects of opioids on μ-receptors in the
gastrointestinal tract, reducing bowel tone, contractility, and luminal fecal
moisture.
Epidemiology-
The prevalence of
opioid-induced constipation (OIC) was 12.6%. Opioid-induced constipation (OIC)
accounts for over 40% to 60% of patients without cancer receiving opioids.
The competitive landscape of Opioid-Induced
Constipation (OIC) includes country-specific approved as well as pipeline
therapies. Any asset/product-specific designation or review and Accelerated
Approval are being tracked and supplemented with analyst commentary.
KOLs insights of Opioid-Induced
Constipation (OIC) across 8 MM market from the centre of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Opioid-Induced
Constipation (OIC) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 Linaclotide Forest
Laboratories Phase 2
2 SP-333 Bausch Health
Americas, Inc. Phase 2
3 Naldemedine Shionogi Phase 2
4 ADL5945 Cubist
Pharmaceuticals LLC Phase 2
5 TD-1211 Theravance
Biopharma Phase 2
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