Adrenocortical insufficiency (AI) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Adrenal insufficiency (AI) or Addison’s disease is a rare disorder characterized by inadequate cortisol and aldosterone production. The symptoms of classic Addison’s disease, also known as primary adrenal insufficiency, result from the insufficient production of these two hormones, cortisol and aldosterone. Diagnosis measures the adrenal corticosteroid hormones, their regulatory peptide hormones, and stimulation tests. It is classified as primary adrenal insufficiency (PAI) or secondary adrenal insufficiency (SAI). PAI results from intrinsic disease to the adrenal cortex, most commonly due to autoimmune adrenalitis. Due to pituitary disease, SAI is caused by insufficient or deficient corticotropin production. The most common cause of adrenal insufficiency is glucocorticoid-induced adrenal insufficiency (GIAI), a unique form of SAI caused by long-term iatrogenic glucocorticoid use.
In the USA, the prevalence of Adrenal
insufficiency (AI) ranges between 55 to
140 cases per million population.
The competitive
landscape of Adrenocortical insufficiency (AI) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Adrenocortical
insufficiency (AI) across 8 MM market
from the center of Excellence/ Public/ Private hospitals participated in the
study. Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm, and Unmet needs.
Adrenocortical
insufficiency (AI) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Hydrocortisone Shire Phase 2/3
2 Infacort® Diurnal
Limited Phase 3
3 Mifepristone Corcept
Therapeutics Phase 2
4 MIN-102 Minoryx
Therapeutics, S.L. Phase 2/3
5 MD1003 MedDay
Pharmaceuticals SA Phase 2/3
6 hematopoietic stem cell infusion Talaris Therapeutics Inc. Phase
1/2
7 VK0214 Viking
Therapeutics, Inc. Phase 1
8 Cholic Acids Travere
Therapeutics, Inc. Phase 3
9 Alkindi EffRx
Pharmaceuticals SA Phase 3
Comments
Post a Comment