Neuroblastoma (NB) – Epidemiology Insights and Forecast Report – 2020 To 2040

Neuroblastoma (NB) Epidemiology Insights

Thelansis’s “Neuroblastoma (NB) Epidemiology Insights and Forecast Report – 2020 To 2040″ provides an analysis of disease burden, characterized by disease definition, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies.

Neuroblastoma (NB) Overview

Neuroblastoma is a malignant tumor of neural crest-derived sympathetic cells, primarily affecting children under 5. It may occur sporadically or in familial cases linked to ALK or PHOX2B mutations (autosomal dominant). Prognosis is strongly influenced by MYCN amplification and chromosomal aberrations. BARD1 and LIN28B polymorphisms are associated with susceptibility. Diagnosis relies on urinary catecholamine metabolites (HVA, VMA), CT/MRI imaging, and MIBG scintigraphy for metastasis. Bone marrow biopsy is used for staging. Differential diagnoses include Wilms tumor. Clinical signs may mimic orthopedic or trauma-related conditions. Treatment involves surgery, chemotherapy, radiotherapy, and immunotherapy (anti-GD2). Despite aggressive therapy, high-risk metastatic disease in children >18 months carries a poor prognosis (~40–50% survival).

Geography coverage:

G8 (United States, EU5 [France, Germany, Italy, Spain, U.K.], Japan, and China)

Deliverables format and updates*:

  • Access to an interactive epidemiology platform with downloadable Excel and PPT files.
    • Global findings
    • G8 findings
    • Regional findings
    • Country-specific findings
  • Others*: regular updates, customizations, epidemiologist support

*As per Thelansis’s policy, we ensure that we include all the recent updates before releasing the content. Countries, subpopulations, and years of forecast can be customized as per client requirements.

Key business questions answered:

  • 20-year historical and forecast data (2020–2040)
  • Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes)
  • Granular patient population coverage by year and geography
  • Detailed segmentation by age, gender, subpopulations, comorbidities, line of therapies, etc.
  • Patient funnels
  • Country comparisons
  • Relevant clinical variables (e.g., staging/classification/severity)

Insights driven by robust research and estimates:

  • Published literature (e.g., peer-reviewed journal articles, registries, national surveys)
  • Primary market research with KOLs
  • RWD analysis using claims and EHR datasets
  • Proprietary mathematical models (e.g., incidence-survival model; incidence- recurrence/progression-survival model)


Read more: Neuroblastoma (NB) – Epidemiology Insights and Forecast Report – 2020 To 2040


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