Chondrosarcoma – Market outlook, Epidemiology, Market Forecast and Competitive Landscape Report – 2020 To 2030
Chondrosarcoma is a rare malignant tumor
that forms a cartilaginous matrix. Chondrosarcomas arising de novo are termed
primary chondrosarcomas, while those developing in pre-existing benign
cartilaginous tumors such as osteochondroma or enchondroma are referred to as
secondary chondrosarcomas. CHS constitutes various groups of malignant bone
tumors and encompasses multiple histological subtypes. Overall, conventional
CHS is the most common subtype. It accounts for 85% of CHS, followed by dedifferentiated
(10%), mesenchymal and clear cell CHS, these two representing less than 2% of
all CHS cases. Conventional CHS can develop de novo or in a pre-existing
enchondroma and osteochondroma. CHS is classified into three grades based on
cellular atypia, mitotic figures, and cellularity. CHS grades 1 and 2 are
represented by 85% of all CHSs, 15% of cases are grade 3, and the
dedifferentiated CHS. According to the latest WHO recommendations, CHS should
be classified into central or secondary peripheral atypical cartilaginous
tumor/CHS (grade 1), central or secondary peripheral CHS grade 2 and 3.
- The estimated overall incidence is 1 per 200,000/year and accounts for 20–30% of primary malignant bone tumors. The majority of cases occur after age 50, with a slight male predominance. The incidence of pediatric chondrosarcoma is less than 10% of all chondrosarcoma cases, with higher survival rates than adults.
The competitive
landscape of Chondrosarcoma includes country-specific approved as well as
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are being tracked and supplemented with analyst
commentary.
KOLs
insights of Chondrosarcoma across 8 MM market from the center of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm, and Unmet needs.
Chondrosarcoma
Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 pazopanib George
Clinical Pty Ltd Phase 2
2 INBRX-109 Inhibrx,
Inc. Phase 2
3 Trabectedin PharmaMar Phase 2
4 AG-120 Agios Pharmaceuticals,
Inc. Phase 2
5 Perifosine AEterna
Zentaris Phase 2
6 LY3410738 Loxo
Oncology, Inc. Phase 1
7 Enasidenib Celgene Phase 2
8 IGM-8444 IGM
Biosciences, Inc. Phase 1
9 FT-2102 Forma
Therapeutics, Inc. Phase 2
10 INBRX-109 Inhibrx,
Inc. Phase 1
Continued...
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