Relapsed / Refractory B-Acute Lymphocytic Leukemia (ALL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034
Relapsed / Refractory B-Acute Lymphocytic Leukemia (ALL) Market Outlook
Thelansis’s “Relapsed / Refractory
B-Acute Lymphocytic Leukemia (ALL) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2024 To 2034" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Relapsed
/ Refractory B-Acute Lymphocytic Leukemia (ALL) treatment modalities options for eight major
markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
Relapsed /
Refractory B-Acute Lymphocytic Leukemia (ALL) Overview
B-Cell
Acute lymphoblastic leukemia (ALL) is a type of blood cancer in which many
abnormal, immature lymphocytes known as blasts begin to multiply in the bone
marrow. Lymphocytes are white blood cells that play a role in the immune
response. B-ALL is characterized by the expression of various B–cell-specific
antigens, which often include PAX-5, CD19, CD20, CD22, CD24, and CD79a. B-cell
ALL is primarily a childhood disease, with approximately 75% of cases being
children aged <6 years, however, the majority of the B-Cell ALL occurs in
the <15 years of age; also, the peak of the incidence is seen in people
around 40 years. Approximately 20% to 30% of adult acute lymphoblastic
leukemias (ALLs) and 5% of pediatric ALLs harbor the Ph-chromosome. This
genetic alteration confers a poor prognosis, as defined by shorter remission
duration and shorter survival, and higher rates of resistance to standard
chemotherapy. CNS involvement is more common in relapsed adult patients. In
children, the overall complete remission rate is greater than 95%, and in
adults, the rate is 60-85 percent. Relapse occurs in 15 to 20% of children with
B-cell ALL, and the prognosis becomes less favorable. Adults with B-cell ALL
have a relapse rate of approximately 50%, and a poor prognosis is expected,
with a median survival of fewer than six months after relapse.
Geography
coverage:
G8 (United States,
EU5 [France, Germany, Italy, Spain, U.K.], Japan, and China)
Insights driven
by robust research, including:
- In-depth interviews with leading
KOLs and payers
- Physician surveys
- RWE analysis for claims and EHR
datasets
- Secondary research (e.g.,
peer-reviewed journal articles, third-party research databases)
Deliverables
format and updates*:
- Detailed Report (PDF)
- Market Forecast Model (MS
Excel-based automated dashboard)
- Epidemiology (MS Excel; interactive
tool)
- Executive Insights (PowerPoint
presentation)
- Others: regular updates,
customizations, consultant support
*As per
Thelansis’s policy, we ensure that we include all the recent updates before
releasing the report content and market model.
Salient
features of Market Forecast model:
- 10-year market forecast (2024–2034)
- Bottom-up patient-based market
forecasts validated through the top-down sales methodology
- Covers clinically and
commercially-relevant patient populations/ line of therapies
- Annualized drug-level sales and
patient share projections
- Utilizes our proprietary Epilansis and Analog tool
(e.g., drug uptake and erosion) datasets and conjoint analysis approach
- Detailed methodology/sources
& assumptions
- Graphical and tabular outputs
- Users can customize the model based
on requirements
Key business
questions answered:
- How can drug development and
lifecycle management strategies be optimized across G8 markets (US, EU5,
Japan, and China)?
- How large is the patient population
in terms of incidence, prevalence, segments, and those receiving drug
treatments?
- What is the 10-year market outlook
for sales and patient share?
- Which events will have the greatest
impact on the market’s trajectory?
- What insights do interviewed experts
provide on current and emerging treatments?
- Which pipeline products show the
most promise, and what is their potential for launch and future
positioning?
- What are the key unmet needs and KOL
expectations for target profiles?
- What key regulatory and payer
requirements must be met to secure drug approval and favorable market
access?
- and more…
Comments
Post a Comment