Infantile Spasms (IS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034

Infantile Spasms (IS) Market Outlook

Thelansis’s “Infantile Spasms (IS) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Infantile Spasms (IS)   treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Infantile Spasms (IS) Overview

Infantile spasms, also known as West syndrome, represent a distinct and often devastating form of epilepsy affecting infants. It is characterized by unique seizure episodes called infantile spasms, which manifest as flexor, extensor, or mixed flexor-extensor spasms. These spasms are accompanied by a distinctive electroencephalography (EEG) pattern known as hypsarrhythmia and developmental delays or regressions. The syndrome can be categorized into two types based on etiology: symptomatic and cryptogenic. Symptomatic cases are associated with identifiable underlying causes or significant developmental delays preceding the onset of spasms. In contrast, cryptogenic cases lack such clear underlying causes and typically involve normal development before spasms onset. Causes of infantile spasms may stem from prenatal, perinatal, or postnatal factors, with approximately half of the cases attributed to prenatal factors, including central nervous system malformations, intrauterine insults, neurocutaneous syndromes such as tuberous sclerosis complex (TSC), metabolic disorders, and genetic syndromes like Down syndrome. Treatment options for infantile spasms include two medications, adrenocorticotropic hormone (ACTH) and vigabatrin, both supported by strong evidence of efficacy. Older drugs such as phenobarbital, carbamazepine, or phenytoin are seldom effective in managing this condition.

 

Geography coverage:

G8 (United States, EU5 [France, Germany, Italy, Spain, U.K.], Japan, and China)

Insights driven by robust research, including:

  • In-depth interviews with leading KOLs and payers
  • Physician surveys
  • RWE analysis for claims and EHR datasets
  • Secondary research (e.g., peer-reviewed journal articles, third-party research databases)

Deliverables format and updates*:

  • Detailed Report (PDF)
  • Market Forecast Model (MS Excel-based automated dashboard)
  • Epidemiology (MS Excel; interactive tool)
  • Executive Insights (PowerPoint presentation)
  • Others: regular updates, customizations, consultant support

*As per Thelansis’s policy, we ensure that we include all the recent updates before releasing the report content and market model.

Salient features of Market Forecast model:

  • 10-year market forecast (2024–2034)
  • Bottom-up patient-based market forecasts validated through the top-down sales methodology
  • Covers clinically and commercially-relevant patient populations/ line of therapies
  • Annualized drug-level sales and patient share projections
  • Utilizes our proprietary Epilansis and Analog tool (e.g., drug uptake and erosion) datasets and conjoint analysis approach
  • Detailed methodology/sources & assumptions
  • Graphical and tabular outputs
  • Users can customize the model based on requirements

Key business questions answered:

  • How can drug development and lifecycle management strategies be optimized across G8 markets (US, EU5, Japan, and China)?
  • How large is the patient population in terms of incidence, prevalence, segments, and those receiving drug treatments?
  • What is the 10-year market outlook for sales and patient share?
  • Which events will have the greatest impact on the market’s trajectory?
  • What insights do interviewed experts provide on current and emerging treatments?
  • Which pipeline products show the most promise, and what is their potential for launch and future positioning?
  • What are the key unmet needs and KOL expectations for target profiles?
  • What key regulatory and payer requirements must be met to secure drug approval and favorable market access?
  • and more…


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