Idiopathic Membranous Nephropathy (IMN) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034

 Idiopathic Membranous Nephropathy (IMN) Market Outlook

Thelansis’s “Idiopathic Membranous Nephropathy (IMN) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Idiopathic Membranous Nephropathy (IMN) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Idiopathic Membranous Nephropathy (IMN) Overview

Membranous nephropathy (MN), also known as membranous glomerulonephritis, is a chronic glomerular disease characterized by specific morphological features observed through light, immunofluorescence (IF), and electron microscopy (EM) analysis of renal tissue. These features include thickening the glomerular basement membrane (GBM) and GBM spikes. Immunostaining reveals granular deposits of IgG and complement along the periphery of glomerular capillary loops, while electron microscopy shows electron-dense subepithelial deposits corresponding to the observed granular IgG staining. MN can be classified into idiopathic or primary MN (IMN or PMN) when secondary factors cannot be identified. IMN, the primary form of MN, is believed to be mediated by IgG antibodies that target podocytes, with IgG4 being the predominant subclass. Several podocyte auto-antigens have been identified in adult IMN, including the M-type receptor for secretory phospholipase A2 (PLA2R1), thrombospondin type-1 domain-containing 7A (THSD7A), and neural epidermal growth factor-like 1 protein (NELL-1). These antigens account for approximately 70-80%, 3-5%, and 5-10% of IMN cases. Recurrence of IMN is observed in approximately half of kidney allograft recipients, resulting in graft dysfunction and failure.

 

Geography coverage:

G8 (United States, EU5 [France, Germany, Italy, Spain, U.K.], Japan, and China)

Insights driven by robust research, including:

  • In-depth interviews with leading KOLs and payers
  • Physician surveys
  • RWE analysis for claims and EHR datasets
  • Secondary research (e.g., peer-reviewed journal articles, third-party research databases)

Deliverables format and updates*:

  • Detailed Report (PDF)
  • Market Forecast Model (MS Excel-based automated dashboard)
  • Epidemiology (MS Excel; interactive tool)
  • Executive Insights (PowerPoint presentation)
  • Others: regular updates, customizations, consultant support

*As per Thelansis’s policy, we ensure that we include all the recent updates before releasing the report content and market model.

Salient features of Market Forecast model:

  • 10-year market forecast (2024–2034)
  • Bottom-up patient-based market forecasts validated through the top-down sales methodology
  • Covers clinically and commercially-relevant patient populations/ line of therapies
  • Annualized drug-level sales and patient share projections
  • Utilizes our proprietary Epilansis and Analog tool (e.g., drug uptake and erosion) datasets and conjoint analysis approach
  • Detailed methodology/sources & assumptions
  • Graphical and tabular outputs
  • Users can customize the model based on requirements

Key business questions answered:

  • How can drug development and lifecycle management strategies be optimized across G8 markets (US, EU5, Japan, and China)?
  • How large is the patient population in terms of incidence, prevalence, segments, and those receiving drug treatments?
  • What is the 10-year market outlook for sales and patient share?
  • Which events will have the greatest impact on the market’s trajectory?
  • What insights do interviewed experts provide on current and emerging treatments?
  • Which pipeline products show the most promise, and what is their potential for launch and future positioning?
  • What are the key unmet needs and KOL expectations for target profiles?
  • What key regulatory and payer requirements must be met to secure drug approval and favorable market access?
  • and more…


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