Catheter-related Bloodstream Infection (CRBSI) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034
Catheter-related Bloodstream Infection (CRBSI) Market Outlook
Thelansis’s “Catheter-related
Bloodstream Infection (CRBSI) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2024 To 2034" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Catheter-related
Bloodstream Infection (CRBSI) treatment modalities options for eight major
markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
Catheter-related Bloodstream Infection
(CRBSI) Overview
Catheter-related
bloodstream infection (CRBSI) refers to the presence of bacteremia originating
from an intravenous catheter. It is a common, severe, and expensive
complication of central venous catheterization and is the leading cause of
nosocomial bacteremia. Intravascular catheters are vital in modern medical
practices, being used in critically ill patients for various purposes such as
administering fluids, blood products, medication, nutritional solutions, and
monitoring hemodynamics. Among all medical devices, central venous catheters
(CVCs) carry the highest risk of device-related infections and contribute
significantly to morbidity and mortality. They are also the primary source of
bacteremia and septicemia in hospitalized patients. Several potential risk
factors contribute to the development of CRBSI, including underlying diseases,
method and site of catheter insertion, duration of catheterization, and the
purpose of catheterization. The use of intravascular catheters for parenteral
nutrition increases the risk of CRBSI. The catheter itself can be involved in
four different pathways leading to infection: colonization of the catheter tip
and cutaneous tract by skin flora, colonization of the catheter lumen due to
contamination, hematogenous seeding of the catheter from another infected site,
and contamination of the catheter lumen with infusate. Gram-positive pathogens
accounted for 64% of CRBSI cases, while Gram-negative pathogens accounted for
36%. The most common pathogens causing CRBSI were Staphylococcus aureus (40%),
Pseudomonas aeruginosa (16%), coagulase-negative staphylococci (8%),
Escherichia coli (8%), Klebsiella pneumoniae (8%), and Acinetobacter baumannii
(4%). The choice of initial antibiotics for treating CRBSI depends on the
severity of the patient’s clinical condition, risk factors for infection, and
the likely pathogens associated with the specific intravascular device.
Geography coverage:
G8 (United States, EU5 [France,
Germany, Italy, Spain, U.K.], Japan, and China)
Insights driven by robust
research, including:
- In-depth interviews with leading KOLs and payers
 - Physician surveys
 - RWE analysis for claims and EHR datasets
 - Secondary research (e.g., peer-reviewed journal
     articles, third-party research databases)
 
Deliverables format and
updates*:
- Detailed Report (PDF)
 - Market Forecast Model (MS Excel-based automated
     dashboard)
 - Epidemiology (MS Excel; interactive tool)
 - Executive Insights (PowerPoint presentation)
 - Others: regular updates, customizations, consultant
     support
 
*As per Thelansis’s policy, we
ensure that we include all the recent updates before releasing the report
content and market model.
Salient features of Market
Forecast model:
- 10-year market forecast (2024–2034)
 - Bottom-up patient-based market forecasts validated
     through the top-down sales methodology
 - Covers clinically and commercially-relevant patient
     populations/ line of therapies
 - Annualized drug-level sales and patient share
     projections
 - Utilizes our proprietary Epilansis and Analog tool
     (e.g., drug uptake and erosion) datasets and conjoint analysis approach
 - Detailed methodology/sources & assumptions
 - Graphical and tabular outputs
 - Users can customize the model based on requirements
 
Key business questions answered:
- How can drug development and lifecycle management
     strategies be optimized across G8 markets (US, EU5, Japan, and China)?
 - How large is the patient population in terms of
     incidence, prevalence, segments, and those receiving drug treatments?
 - What is the 10-year market outlook for sales and
     patient share?
 - Which events will have the greatest impact on the
     market’s trajectory?
 - What insights do interviewed experts provide on
     current and emerging treatments?
 - Which pipeline products show the most promise, and
     what is their potential for launch and future positioning?
 - What are the key unmet needs and KOL expectations for
     target profiles?
 - What key regulatory and payer requirements must be
     met to secure drug approval and favorable market access?
 - and more…
 
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