Leber’s Hereditary Optic Neuropathy (LHON) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Leber's
hereditary optic neuropathy (LHON) is characterized by rapid bilateral loss of
central vision. Primarily male patients are affected in early adult life. Optic
atrophy commonly appears within 3 months after the onset of the disease.
Relatives in the maternal line often show peripapillary microangiopathy typical
for LHON. In most cases, symptoms begin with one eye first, followed a few
weeks later by visual failure in the other eye. Extremely rarely there may be
neurologic abnormalities, such as peripheral neuropathy, postural tremor,
nonspecific myopathy, and movement disorders. LHON is caused by mutations in
mitochondrial DNA and is strictly transmitted by maternal inheritance. The
acute phase of LHON is characterized by a loss of central vision, including
blurring and reduced perception of color. Individuals usually lose vision in
one eye first and then lose vision in the other eye after two to three months.
The atrophic phase is characterized by bilateral optic atrophy, resulting in
lifelong blindness.
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According to Thelansis disease area data
modeling the prevalence of LHON is ranges between 1to 1.4 cases per 45,000,
while the incidence of LHON is 1.2 in 1,000,000 population.
Thelansis’s
“Leber’s Hereditary Optic Neuropathy (LHON) Market Outlook, Epidemiology,
Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers
disease overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Leber’s
Hereditary Optic Neuropathy (LHON) treatment modalities options for eight major
markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Leber’s Hereditary
Optic Neuropathy (LHON) across 8 MM market from the centre of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm, and Unmet needs.
Leber’s
Hereditary Optic Neuropathy (LHON) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Leber’s
Hereditary Optic Neuropathy (LHON), Leber’s Hereditary Optic Neuropathy (LHON) market outlook, Leber’s Hereditary Optic Neuropathy
(LHON) competitive landscape, Leber’s
Hereditary Optic Neuropathy (LHON) market forecast,
Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)
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