IgG4-related Disease – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

IgG4-related disease (IgG4-RD) is a multi-organ disorder that presents clinical and histopathological features similar to malignant, infectious, and inflammatory conditions. The disease exhibits a tumefactive clinical presentation consistent across multiple organ systems, except for the aorta, meninges, and bile ducts, in which the sclerosing nature of the disease predominates. The most common presentation is diffuse, or focal pseudotumoral swelling of an organ discovered clinically or radiologically, along with enlarged lymph nodes that are often painless and hard. The onset of the disease is usually subacute and asymptomatic, and common manifestations include fever, weight loss, or increased inflammatory parameters, which are present in only a minority of patients. The incidence of extrapancreatic manifestations, such as mediastinal or abdominal lymphadenopathy and involvement of the lacrimal or salivary glands, kidneys, lungs, and retroperitoneum, varies, with pancreatitis being the most common manifestation, and bile duct involvement is present in 74% of cases. HLA serotypes DRB10405 and DQB10401 have been identified as genetic susceptibility factors in Japanese populations. Other susceptibility factors include single-nucleotide polymorphisms in cytotoxic T-lymphocyte–associated antigen 4, tumor necrosis factor-alpha, and Fcreceptor–like 3. Differentiation of IgG4-RD from malignant tumors is crucial, as common mimics include Sjögren's syndrome, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome), sarcoidosis, and multicentric Castleman's disease.

 

Thelansis’s “IgG4-related Disease Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential IgG4-related Disease treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of IgG4-related Disease across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

IgG4-related Disease Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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