Familial Partial Lipodystrophy (FPLD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Familial Partial Lipodystrophy (FPLD) syndromes are a heterogeneous group of genetically inherited or acquired conditions characterized by dysfunctional white adipose tissue. It is characterized by selective loss of adipose tissue in the extremities and gluteal region without changing abdominal and visceral fat. In most cases, abnormal fat distribution becomes apparent at puberty. This selective deficiency of metabolically active adipose tissue is tightly linked with a wide range of metabolic complications, such as insulin resistance, lipoatrophic diabetes, dyslipidemia with severe hypertriglyceridemia, hypertension, or hepatic steatosis. Moreover, female patients often develop hyperandrogenism, hirsutism, polycystic ovaries, and infertility. The extent of fat loss often determines the severity of metabolic consequences. There are seven subtypes of FPLD caused by mutations in various genes (LMNA, PPARG, PLIN1, CIDEC, LIPE, AKT2 or CAV1); the condition can be inherited in either a dominant (mostly) or recessive manner. Variants within the LMNA and PPARG genes account for more than 50% of all reported FPLD cases. Both genes are crucial in adipose tissue's differentiation and proper functioning. The most common form of FPLD is type 2, inherited in an autosomal dominant manner.

  • The incidence of Familial Partial Lipodystrophy (FPLD) syndromes ranges from 1 to 1.5 cases per million population in the USA.

 

Thelansis’s “Familial Partial Lipodystrophy (FPLD) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Familial Partial Lipodystrophy (FPLD) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Familial Partial Lipodystrophy (FPLD) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Familial Partial Lipodystrophy (FPLD) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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