Radioiodine-Refractory Differentiated Thyroid Cancer – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 Radioactive iodine I-131 (RAI) treatment is the primary systemic therapy for advanced disease (5). It frequently leads to a cure in young patients with small metastases arising from well-differentiated thyroid cancer, particularly those exhibiting high RAI uptake in neoplastic foci. This subgroup constitutes approximately one-third of advanced thyroid cancer patients. However, in the remaining two-thirds of advanced cases, achieving a cure is a rare occurrence. These patients will eventually be classified as refractory. RAI is a pivotal component of standard adjuvant treatment for individuals with high-risk differentiated thyroid cancer (DTC). Nevertheless, 5% to 15% of DTC cases and a striking 50% of metastatic DTC cases exhibit refractoriness to RAI treatment. Those diagnosed with RAI-refractory (RAI-R) thyroid cancer face a grim prognosis, with 5-year disease-specific survival rates ranging from 60% to 70%. The outlook is even bleaker for those with RAI-R metastatic thyroid cancer, who exhibit a mere 10% 10-year survival rate. RAI refractoriness is most commonly associated with the loss of thyroid differentiation features. A clear indicator of dedifferentiation is the dysfunction of the Na/I symporter (NIS). Standard protocols for identifying recurrent and metastatic DTC following total/near total thyroidectomy and RAI therapy involve serum thyroglobulin (Tg) tests in conjunction with RAI whole body scans (WBS).

·       According to Thelansis disease modeling data, literature reviews, surveys, and registry analyses, 8% to 17% of thyroid cancer (TC) patients develop distant metastases, with one-third becoming radioiodine-refractory (RAIR).

 

Thelansis’s “Radioiodine-Refractory Differentiated Thyroid Cancer Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Radioiodine-Refractory Differentiated Thyroid Cancer treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Radioiodine-Refractory Differentiated Thyroid Cancer across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Radioiodine-Refractory Differentiated Thyroid Cancer Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Radioiodine-Refractory Differentiated Thyroid Cancer – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Radioiodine-Refractory Differentiated Thyroid Cancer, Radioiodine-Refractory Differentiated Thyroid Cancer market outlook, Radioiodine-Refractory Differentiated Thyroid Cancer competitive landscape, Radioiodine-Refractory Differentiated Thyroid Cancer market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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