Ocular Myasthenia Gravis (OMG) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Ocular myasthenia gravis (OMG) is an autoimmune disorder characterized by weakness of the extraocular eye muscles, levator palpebrae superioris, and orbicularis oculi, resulting in ptosis and diplopia. It primarily affects the ocular muscles without involving other muscle groups. Ocular manifestations are common in myasthenia gravis, occurring in 15-50% of cases, with fluctuating ptosis, diplopia, and orbicular weakness being the most frequent symptoms. OMG primarily presents with ptosis or diplopia due to ophthalmoplegia, with the hallmark features of fatigability and variability. Clinical examination often confirms these characteristics. Ptosis may affect one or both eyelids, and the upper eyelid elevator muscle exhibits fatigability during sustained upgaze. Enhanced ptosis, known as the "curtain effect," occurs when one eyelid is lifted, and the contralateral eyelid develops or worsens existing ptosis. Several tests are employed to diagnose ocular myasthenia gravis, including sleep, ice, antibody, edrophonium, neostigmine, repetitive nerve stimulation, electrical nerve testing, and scanning. OMG can mimic other pupil-sparing ocular motility disorders, such as fourth, sixth, and partial third nerve palsies, central gaze disorders like internuclear ophthalmoplegia, the one-and-a-half syndrome, and chronic progressive external ophthalmoplegia. Treatment for OMG is determined based on the severity of symptoms during presentation. If myasthenia gravis remains confined to ocular symptoms for one year, the likelihood of progression to generalized myasthenia gravis is 16%. However, if the disease remains localized for three years, the possibility of progression decreases to only 6%.

  • The estimated annual incidence of OMG in the United States is 1.13 per 100,000 individuals.

Thelansis’s “Ocular Myasthenia Gravis (OMG) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Ocular Myasthenia Gravis (OMG) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Ocular Myasthenia Gravis (OMG) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Ocular Myasthenia Gravis (OMG) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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