Guillain-Barre Syndrome (GBS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Guillain-Barre Syndrome (GBS) is a type of acute paralytic neuropathy that is both common and severe. Typically involves progressive limb weakness accompanied by decreased or absent reflexes. However, some patients experience localized weakness or other symptoms, such as facial diplegia or paraesthesia. GBS is also associated with several other disorders, such as Miller-Fisher syndrome and Bickerstaff brainstem encephalitis. These conditions can share similar biomarkers but present with different clinical features. GBS can be broadly classified into two types: acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and acute motor axonal neuropathy (AMAN), based on the site of the target antigen. The underlying mechanisms of GBS involve both innate and adaptive immunity. Innate immunity is associated with dendritic cells, complement fractions, mast cells, and specific toll-like receptors. Adaptive immunity is characterized by IL17 and IL22 secretion, anomalies in CD4(+)CD25(+) regulator T-cells, and anti-ganglioside and anti-nodes of Ranvier protein IgG. GBS is triggered by various factors, including infections by viruses such as dengue, hepatitis E, and Zika, as well as cross-reactivity phenomena in cases of Campylobacter jejuni diarrhea. Factors that affect prognosis include older age, rapid disease progression, diarrhea as a triggering factor, and the need for mechanical ventilation. Clinical scores such as EGRIS can be used to assess the short-term risk of intubation, and the EGOS and mEGOS can be used to determine the capacity to walk at six months or four weeks, respectively.
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Estimate incidence rates of Guillain-Barre
Syndrome in Europe and North America showed a similar range of 1 to 2 cases per
100000 population per year.
Thelansis’s
“Guillain-Barre Syndrome (GBS) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2023 To 2033" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Guillain-Barre
Syndrome (GBS) treatment modalities options for eight major markets (USA,
Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Guillain-Barre
Syndrome (GBS) across 8 MM market from the centre of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Guillain-Barre
Syndrome (GBS) Market Forecast Patient Based Forecast Model (MS.
Excel Based Automated Dashboard), which Data Inputs with sourcing, Market
Event, and Product Event, Country specific Forecast Model, Market uptake and
patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and
pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Guillain-Barre
Syndrome (GBS), Guillain-Barre Syndrome (GBS) market
outlook, Guillain-Barre Syndrome (GBS) competitive
landscape, Guillain-Barre Syndrome (GBS) market
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Intelligence (CI)
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