Goitre – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Goiter, an enlargement of the thyroid gland, can arise from various causes. The primary cause, accounting for over 90% worldwide, is iodine deficiency in the diet, resulting in a simple goiter. Numerous pathogenic mechanisms underlie goiter formation. One prominent factor is iodine deficiency, particularly in regions lacking public health interventions to counter it, termed endemic goiter. Additionally, inflammatory thyroid gland disorders such as autoimmune thyroiditis, postpartum thyroiditis, silent thyroiditis, radiation thyroiditis, subacute thyroiditis, and suppurative thyroiditis can induce thyroid enlargement, leading to goiter. In these cases, the term "goiter" isn't used to characterize the disorder, as the enlargement stems from the inflammatory process and subsides once inflammation resolves. Instead, goiter becomes one among several symptoms of inflammatory thyroid disorders. Conditions like Grave's disease, toxic nodular goiter, and toxic multinodular goiter, causing hyperthyroidism, can also lead to goiter formation. This goiter can encompass single or multiple nodules and is known as nodular goiter or nontoxic multinodular goiter, often associated with normal thyroid function. Other triggers encompass thyroid cancer, granulomatous disorders, and infiltrative thyroid diseases. Thyroid enlargement or goiter emerges as an adaptive reaction of thyroid follicular cells to disruptions in thyroid hormone production. The predominant cause remains iodine deficiency, although Hashimoto's thyroiditis becomes significant in iodized salt-consuming countries or those without iodine deficiency issues. Nevertheless, iodine deficiency remains the prevalent global cause. Goiters exhibit diverse morphological, hormonal, and clinical manifestations, and not all are linked to iodine deficiency, with genetic, demographic, and environmental factors contributing. Simple goiter generally carries a favorable prognosis. However, substantial enlargement may lead to compression of adjacent structures, resulting in breathing difficulties, swallowing challenges, and hoarseness. It's vital to distinguish between benign and malignant thyroid enlargement causes. Surgical intervention becomes an option if the goiter continues to grow. The prognosis for goiter associated with conditions like Grave's disease or Hashimoto's thyroiditis hinges on the underlying cause of thyroid enlargement. Consequences of goiter encompass hypothyroidism, hyperthyroidism, further enlargement, retrosternal extension, nodule formation, and thyroid cancer detection. These manifestations constitute goiter-associated presentations or clinical entities and are not classified as complications. Potential complications of simple goiter include tracheal compression with tracheomalacia, the Iodo-Basedow phenomenon (inducing hyperthyroidism upon iodine exposure), and intra-nodular hemorrhage or necrosis. Benign goiters can be managed with thyroid hormone therapy. Levothyroxine sodium, taken once daily, is the most widely employed thyroid hormone. Liothyronine sodium requires more frequent dosing. Desiccated thyroid powder, thyroglobulin, and liotrix yield less predictable results upon ingestion.
- Estimates suggest that goiters affect around 200 million individuals among the 800 million with iodine-deficient diets.
Thelansis’s “Goitre Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Goitre treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Goitre across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Goitre Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
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