Community-Acquired Pneumonia (CAP) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Community-acquired pneumonia (CAP) denotes an acute infection affecting the pulmonary parenchyma in individuals devoid of recent hospitalization within 14 days and not residing in nursing homes or long-term care facilities. The etiology of CAP encompasses two broad categories: Typical agents (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, Group A Streptococci, anaerobes, and gram-negative organisms) and Atypical agents (e.g., Legionella, Mycoplasma, Chlamydia pneumoniae, and C. psittaci), with H. influenzae and S. pneumoniae commonly implicated as bacterial causative agents. Pharyngeal colonization by pathogens, followed by micro-aspiration, constitutes the primary mechanism of lower respiratory tract invasion, supplemented by hematogenous dissemination and macro-aspiration. Pneumonia manifests when host pulmonary defenses are compromised or overwhelmed by a substantial pathogen inoculum or virulence. Risk factors for CAP encompass advancing age, chronic comorbidities, notably chronic obstructive pulmonary disease (COPD), chronic lung diseases (e.g., bronchiectasis, asthma), chronic heart diseases (particularly congestive heart failure), stroke, diabetes mellitus, malnutrition, and immunocompromising conditions. Viral respiratory tract infections, especially influenza, predispose individuals to primary viral pneumonia and secondary bacterial pneumonia. Impaired airway protection, exemplified by conditions fostering microaspiration of gastric contents or microaspiration of upper airway secretions (e.g., altered consciousness, dysphagia), heightens CAP susceptibility. Modifiable behavioral risk factors include smoking, excessive alcohol consumption, and opioid use. In contrast, socio-environmental factors such as crowded living conditions, low-income settings, and exposure to environmental toxins also contribute to increased CAP risk. The therapeutic approach for outpatient CAP typically involves monotherapy with a macrolide (e.g., erythromycin, azithromycin, or clarithromycin) or doxycycline. However, in the presence of comorbidities such as chronic heart disease (excluding hypertension), chronic lung disease (including COPD and asthma), chronic liver disease, chronic alcohol use disorder, diabetes mellitus, smoking, splenectomy, human immunodeficiency virus (or other forms of immunosuppression), a respiratory fluoroquinolone (e.g., high-dose levofloxacin, moxifloxacin, gemifloxacin) or a combination of oral beta-lactam (e.g., high-dose amoxicillin or amoxicillin-clavulanate, cefuroxime, cefpodoxime) and macrolide is recommended.
Thelansis’s
“Community-Acquired Pneumonia (CAP) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2023 To 2033" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Community-Acquired
Pneumonia (CAP) treatment modalities options for eight major markets (USA,
Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Community-Acquired
Pneumonia (CAP) across 8 MM market from the centre of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Community-Acquired
Pneumonia (CAP) Market Forecast Patient Based Forecast Model (MS.
Excel Based Automated Dashboard), which Data Inputs with sourcing, Market
Event, and Product Event, Country specific Forecast Model, Market uptake and
patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and
pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Community-Acquired
Pneumonia (CAP), Community-Acquired Pneumonia (CAP) market
outlook, Community-Acquired Pneumonia (CAP) competitive
landscape, Community-Acquired Pneumonia (CAP) market
forecast, Thelansis, Primary market research, KOL insights, Competitive
Intelligence (CI)
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