Ataxia Telangiectasia (AT) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 Ataxia telangiectasia (A-T), also known as Louis-Bar syndrome, is a rare genetic disorder caused by mutations in the ataxia telangiectasia mutated (ATM) gene located on chromosome 11q22-23. These mutations result in a loss of function of the ATM protein, which plays a crucial role in cellular DNA repair, cell cycle control, and cellular response to external triggers such as ionizing radiation and alkylating agents. The clinical manifestation of A-T is characterized by a combination of neurological and systemic symptoms, including cerebellar atrophy with progressive ataxia, cutaneous telangiectasias, increased incidence of malignancy (particularly lymphoid malignancy), radiosensitivity, immune deficiency, recurrent sinopulmonary infections, and high levels of alpha-fetoprotein in serum. The mechanism underlying the formation of telangiectasia, a hallmark of the disorder, remains unknown. The survival of patients with ataxia telangiectasia is greatly affected by attentive care and careful screening, which prevent recurrent infections and early identification of tumors. The median survival for patients with the classical form of A-T is 19-25 years, with wide variability. Atypical forms of the disease usually present with a milder phenotype and a much longer life expectancy. Complications include cognitive impairment, neurologic deficits, increased fall risk, pulmonary disease, recurrent infections, and malignancy.

·       The worldwide prevalence of ataxia telangiectasia is estimated to be between 1 in 40,000 and 1 in 100,000 live births.

 

Thelansis’s “Ataxia Telangiectasia (AT) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Ataxia Telangiectasia (AT) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Ataxia Telangiectasia (AT) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Ataxia Telangiectasia (AT) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Ataxia Telangiectasia (AT) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Ataxia Telangiectasia (AT), Ataxia Telangiectasia (AT) market outlook, Ataxia Telangiectasia (AT) competitive landscape, Ataxia Telangiectasia (AT) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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