Triple-Negative Breast Cancer (TNBC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 Triple-negative breast cancer (TNBC) is a heterogeneous disease encompassing a variety of biomarkers or genomic signatures; it accounts for 12% of all breast cancers in the USA. 1- and 2- year survival rates are 75% and 55%, respectively. Prognosis is poor in the advanced stages – median survival of 13.3 months following diagnosis of metastatic TNBC. Emerging therapies are expected to drive patient stratification for biomarker-defined and pathway-specific (subtyping) patient subgroups - an opportunity for a novel agent in relevant specific segments. TNBC is a clinicopathologic, not intrinsic (genomically defined) subgroup, as neither overexpressing ER and PR nor being HER2+ (IHC and/or FISH). Neither hormonal (endocrine) nor HER2-targeted therapies are indicated potential for FastTrack/ breakthrough designation with promising outcomes in the biomarker-driven patient segment. Several PARP inhibitors are in trials; veliparib+carboplatin followed by chemotherapy showed pCR: 52% vs 26% (chemotherapy alone) 40% of TNBC show overexpression of GPNMB; impressive activity with glembatumumab, a GPNMB-targeting AD Biomarker-driven segments have been identified within TNBC, with POC. A better understanding of these would enable personalized treatment with improved patient outcomes. p53, PTEN, and PIK3CA are most frequently mutated in TNBC (>10%).

·       The mean annual incidence of triple-negative breast cancer (TNBC) across SEAs was 13.7 per 100,000 women.

 

Thelansis’s “Triple-Negative Breast Cancer (TNBC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Triple-Negative Breast Cancer (TNBC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Triple-Negative Breast Cancer (TNBC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Triple-Negative Breast Cancer (TNBC) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Triple-Negative Breast Cancer (TNBC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Triple-Negative Breast Cancer (TNBC), Triple-Negative Breast Cancer (TNBC) market outlook, Triple-Negative Breast Cancer (TNBC) competitive landscape, Triple-Negative Breast Cancer (TNBC) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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