Resistant Hypertension (RH) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Resistant hypertension (RH) is characterized by persistently elevated blood pressure (BP) despite the concurrent administration of three antihypertensive drug classes. These typically include a long-acting calcium channel blocker, a renin-angiotensin system blocker (either an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker), and a diuretic. Additionally, RH encompasses cases where BP reaches target values despite the use of four or more antihypertensive medications. Diagnosis necessitates confirmation of medication adherence and the exclusion of the "white-coat effect," where office BP surpasses the goal but out-of-office BP remains within the target range. Patients with RH face elevated risks of various adverse outcomes. Specifically, they exhibit a 32% heightened risk of developing end-stage renal disease, a 24% increased risk of experiencing an ischemic heart event, a 46% higher likelihood of heart failure, a 14% elevated risk of stroke, and a 6% increased risk of mortality. RH exacerbates outcomes in patients with certain comorbidities. For instance, in individuals with chronic kidney disease (CKD), RH heightens the risk of myocardial infarction, stroke, peripheral arterial disease, heart failure, and all-cause mortality compared to those without RH. Similarly, among patients with ischemic heart disease, RH correlates with elevated rates of adverse events such as death, myocardial infarction, and stroke. Management strategies for RH involve maximizing lifestyle interventions and utilizing long-acting thiazide-like diuretics such as chlorthalidone or indapamide. Furthermore, adding a mineralocorticoid receptor antagonist like spironolactone or eplerenone may be necessary. If BP remains elevated, a stepwise approach to adding antihypertensive drugs with complementary mechanisms of action is recommended to achieve BP reduction.

Thelansis’s “Resistant Hypertension (RH) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Resistant Hypertension (RH) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Resistant Hypertension (RH) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Resistant Hypertension (RH) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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