Myelofibrosis – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Myelofibrosis (MF) is an uncommon, chronic myeloproliferative neoplasm that lacks the BCR-ABL1 mutation. It is characterized by the gradual development of fibrosis in the bone marrow, leading to ineffective hematopoiesis and limited life expectancy. The clinical presentation of MF includes low blood cell counts due to hematopoiesis outside the bone marrow, an enlarged spleen, and various distressing abdominal and overall health-related symptoms. Aberrant Janus kinase (JAK)-signal transducer and activator of transcription signaling are responsible for the secondary effects seen in MF, such as abnormal blood cell production, muscle wasting, systemic symptoms, and bone marrow fibrosis. Serious complications of MF comprise transformation into acute leukemia, bleeding and clotting issues, organ dysfunction, and infections. Allogeneic hematopoietic stem cell transplant (AHSCT) is presently the sole therapeutic approach for MF, capable of extending life and potentially curing the condition in some instances. Nevertheless, transplant-related complications are significant, with a potential for mortality or substantial health problems affecting approximately half of all cases. Conversely, the current pharmaceutical treatment for MF, including the use of JAK2 inhibitors, primarily focuses on alleviating symptoms and has not demonstrated the ability to alter the disease's natural progression or prolong survival. Thelansis' research encompasses both secondary and primary research findings.
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The incidence of MF ranges from 1.7 to 2.4 per
1,00,000 persons, whereas the estimated prevalence in the USA varies from 3.6
to 5.7 per 100,000 persons.
Thelansis’s
“Myelofibrosis Market Outlook, Epidemiology, Competitive Landscape, and Market
Forecast Report – 2023 To 2033" covers disease overview, epidemiology,
drug utilization, prescription share analysis, competitive landscape, clinical
practice, regulatory landscape, patient share, market uptake, market forecast,
and key market insights under the potential Myelofibrosis treatment modalities
options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan,
and China).
KOLs insights of Myelofibrosis across
8 MM market from the centre of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm, and Unmet
needs.
Myelofibrosis
Market Forecast Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Myelofibrosis,
Myelofibrosis market outlook, Myelofibrosis competitive landscape, Myelofibrosis market forecast, Thelansis, Primary market research, KOL
insights, Competitive Intelligence (CI)
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