IgA Nephropathy – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 IgA nephropathy (IgAN) is the most prevalent form of primary glomerulonephritis worldwide. The fundamental issue of this condition lies in the abnormal glycosylation of O-linked glycans (glycoproteins) within the hinge region of IgA1 throughout the body. Consequently, there are increased galactose-deficient IgA1 (GdIgA1) levels in the bloodstream, targeted by glycan-specific IgA and IgG autoantibodies. IgA, an antibody integral to mucosal immunity, occurs in two isotypes, namely IgA1 and IgA2. It can also exist as a dimeric structure known as secretory IgA. Plasma cells mainly produce secretory IgA in a polymeric form, consisting of multiple monomers linked by the J-chain, a 17-kDa polypeptide. In IgAN, the kidneys sustain the primary damage. The disease follows a gradual yet relentless clinical course, leading to end-stage renal disease (ESRD) in approximately 30-40% of patients within 20-30 years. IgAN can manifest in sporadic cases (90-95%) or familial cases (5-10%). Individuals with familial IgAN may experience a more unfavorable prognosis than those with sporadic forms since they are more likely to progress to renal failure. Currently, there are no FDA-approved treatments for IgAN.

·       The annual incidence of IgAN in the United States is 1.29 per 100,000 individuals annually.

 

Thelansis’s “IgA Nephropathy Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential IgA Nephropathy treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of IgA Nephropathy across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

IgA Nephropathy Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: IgA Nephropathy – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: IgA Nephropathy, IgA Nephropathy market outlook, IgA Nephropathy competitive landscape, IgA Nephropathy market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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