Tonic-Clonic Seizures – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Tonic-clonic seizure is characterized by a tonic phase and clonic muscle contractions, which was once referred to as a grand mal seizure. Of all the seizure kinds, they are the most feared by patients, families, and onlookers. They are typically linked to either total loss of consciousness or diminished awareness. In the most recent categorization published by the International League Against Epilepsy (ILAE), they fall within the category of seizures with a generalized onset. Motor and non-motor (absence) seizures are subtypes of generalized onset seizures. The majority of generalized tonic-clonic seizures are caused by underlying hereditary epilepsy, which was previously classified as idiopathic epilepsy. Even if a CT scan is negative, further imaging, such as magnetic resonance imaging (MRI), must be performed if there is a high suspicion of localized abnormality. When a patient experiences focal neurological abnormalities that cannot be explained by a structural abnormality or variable mental state or does not return to baseline 30 to 60 minutes following a seizure, emergency electroencephalography is advised. The first line of treatment are benzodiazepine, such as intramuscular midazolam, intravenous lorazepam, intravenous diazepam, intranasal midazolam or rectal diazepam. Second-line therapy should start if seizures last longer than twenty minutes. One of these three antiepileptic medications is intravenous fosphenytoin, levetiracetam, or valproic acid—which can be administered as a single bolus dosage; however, there is no evidence-based recommended second-line therapy.

  • In the United States, seizures make up 1% to 2% of all emergency room visits. It is estimated that 11% of Americans may experience a seizure at some point in their lifetime. Males are more likely than females to experience acute symptomatic seizures at a ratio of 1.85 to 1, with a lifetime risk of 5.0% for men and 2.7% for women.

Thelansis’s “Tonic-Clonic Seizures Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Tonic-Clonic Seizures treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Tonic-Clonic Seizures across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Tonic-Clonic Seizures Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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