Microvillus Inclusion Disease (MVID) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Microvillus inclusion disease (MVID) is a rare inherited, and invariably deadly enteropathy, characterized by severe, intractable secretory diarrhea and nutrient malabsorption. This diarrhea becomes so abundant that within 24H, the children can lose up to 30% of their body weight, resulting in profound metabolic acidosis and severe dehydration. MVID is diagnosed by evaluating symptoms, excluding more common causes of diarrhea, and evaluating intestinal biopsies. Intestinal biopsies of patients with MVID show villus hypoplasia in the small intestine but no signs of infection or inflammation. MVID is caused by loss of function changes (mutations) in the myosin Vb (Myo5b) gene, a molecular motor gene responsible for the traffic of proteins into the brush border of epithelial cells. Mutations cause most cases of MVID in Myo5b. However, mutations in syntaxin 3, a gene for a SNARE protein responsible for vesicle fusion with the membrane, have been reported in some patients with MVID with late presentation and milder disease.
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Around 350 cases of Microvillus inclusion
disease (MVID) are diagnosed yearly in the USA.
Thelansis’s “Microvillus Inclusion
Disease (MVID) Market Outlook, Epidemiology, Competitive Landscape, and Market
Forecast Report – 2022 To 2032" covers disease overview, epidemiology,
drug utilization, prescription share analysis, competitive landscape, clinical
practice, regulatory landscape, patient share, market uptake, market forecast,
and key market insights under the potential Microvillus Inclusion Disease
(MVID) treatment modalities options for eight major markets (USA, Germany,
France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Microvillus Inclusion Disease (MVID) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Microvillus Inclusion Disease (MVID) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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