Congenital Generalized Lipodystrophy (CGL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032
Congenital Generalized Lipodystrophy (CGL) is a rare autosomal recessive disease characterized by a near complete absence of functional adipose tissue from birth. One of the most ordinary features is insulin resistance, a condition in which the body's tissues cannot recognize insulin, a hormone that usually helps to regulate blood sugar levels. Insulin resistance may develop into a more severe disease called diabetes mellitus. Furthermore, congenital generalized lipodystrophy causes an abnormal fat buildup in the liver (hepatic steatosis), leading to an enlarged liver (hepatomegaly) and liver failure. Some people who are affected develop hypertrophic cardiomyopathy, a type of heart disease that can lead to heart failure and an abnormal heart rhythm (arrhythmia) that can lead to sudden death. People with congenital generalized lipodystrophy have a distinctive physical appearance. They appear very muscular because they have an almost complete absence of adipose tissue and an overgrowth of muscle tissue. A lack of adipose tissue under the skin makes the veins appear prominent. Mutations in the AGPAT2, BSCL2, CAV1, and CAVIN1 genes cause congenital generalized lipodystrophy types 1 through 4, respectively. The proteins produced from these genes play essential roles in the development and function of adipocytes, which are the fat-storing cells in adipose tissue.
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The incidence of Congenital Generalized
Lipodystrophy (CGL) syndromes ranges from 1 to 1.5 cases per ten million
population in the USA.
Thelansis’s “Congenital Generalized
Lipodystrophy (CGL) Market Outlook, Epidemiology, Competitive Landscape, and
Market Forecast Report – 2022 To 2032" covers disease overview,
epidemiology, drug utilization, prescription share analysis, competitive
landscape, clinical practice, regulatory landscape, patient share, market
uptake, market forecast, and key market insights under the potential Congenital
Generalized Lipodystrophy (CGL) treatment modalities options for eight major
markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Congenital Generalized Lipodystrophy (CGL) across 8 MM market from the
centre of Excellence/ Public/ Private hospitals participated in the study.
Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm, and Unmet needs.
Congenital Generalized Lipodystrophy
(CGL) Market
Forecast Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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