Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032


 Ovarian cancer is a type of malignancy that occurs in women. The majority of ovarian cancers, up to 90%, originate from the epithelial cells of the ovary. These cancers can be further classified into subtypes based on their histological and immunohistochemical characteristics, with the most common subtypes being high-grade serous (70%), low-grade serous, high-grade endometrioid, low-grade endometrioid, clear cell, and mucinous carcinomas. Low-grade serous carcinoma of the ovary or peritoneum (LGSC) is a rare subtype, accounting for between 5 and 8% of all ovarian carcinomas. LGSC can develop from a precursor lesion known as a serous borderline ovarian tumor (SBOT) or a de novo malignancy in the ovary or peritoneum. Patients with LGSC may present with non-specific symptoms such as abdominal discomfort, bloating, dyspnea, dyspepsia, and changes in bowel movement patterns. Alternatively, it may arise from the malignant transformation of a borderline ovarian tumor. LGSOC is characterized by being WT1 positive (95%), p53 wild-type (90%), ER-positive (57%), and PR positive (78%). Additionally, LGSOC typically presents with activating mutations in the RAS-RAF-MEK-ERK pathway. The neoplasm usually appears as a solid cystic mass involving the ovarian surface and parenchyma, with sizes ranging from 0.2 cm to over 20 cm. Bilaterality is present in approximately 50% of cases. The contents of the tumor are typically serosanguineous or watery and straw-coloured and less frequently mucinous. Patients with low-grade serous carcinoma tend to be younger than those with high-grade tumors, with a mean age of 45–57 years and 55–65 years, respectively.

·       In China, the ovarian cancer incidence rate was estimated to be 4.2 per 100,000.

Thelansis’s “Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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