Monoclonal Gammopathy of Undetermined Significance (MGUS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032


 Monoclonal gammopathies are a group of disorders characterized by a monoclonal protein in circulation. These disorders encompass a range of entities, from the highly prevalent and asymptomatic monoclonal gammopathy of undetermined significance (MGUS) to more advanced and less frequent conditions such as multiple myeloma. These disorders are classified based on the involved immunoglobulin (M-protein), including non-immunoglobulin M (IgM), IgM, and light chain. The progression rate to multiple myeloma (MM), a lymphoproliferative disorder, amyloidosis, or light-chain deposition disease is 1% per year. Patients with IgM MGUS have an increased risk of developing non-Hodgkin lymphoma, chronic lymphocytic leukemia, light-chain amyloidosis, and Waldenström macroglobulinemia (WM) at a rate of 1.5% per year. The most common heavy-chain subtype in MGUS is IgG, found in approximately 70% of patients, followed by IgM (15%), IgA (12%), and biclonal gammopathy (3%). MGUS is biologically and clinically heterogeneous, with a spectrum of patients who eventually progress and others who have a durably indolent course. The disorder is associated with various complications such as infections, fractures, peripheral neuropathy, thromboembolism, and monoclonal gammopathy of renal significance.

·       In the USA, the incidence of MGUS increases with age, with a prevalence of 3.2% in individuals ≥50 years of age, 5.3% in persons ≥70 years, and 8.9% in men ≥85 years old. MGUS is detected twice as frequently in men than women and three times more often in patients of African descent.

Thelansis’s “Monoclonal Gammopathy of Undetermined Significance (MGUS) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Monoclonal Gammopathy of Undetermined Significance (MGUS) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Monoclonal Gammopathy of Undetermined Significance (MGUS) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Monoclonal Gammopathy of Undetermined Significance (MGUS) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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