Glanzmann Thrombasthenia (GT) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032
Glanzmann Thrombasthenia (GT) is a
genetic bleeding disorder caused by mutations in the ITGA2B or ITGB3 gene. The
disorder results in quantitative and qualitative abnormalities of the integrin
alphaIIb/beta3 (αIIbβ3) receptor protein, which is necessary for platelet
aggregation and clot formation. The deficiency or dysfunction of αIIbβ3 leads
to the inability of platelets to bind together and form clots, causing moderate
to severe bleeding. The disorder has been classified into three types based on
the availability of αIIbβ3. Type I is the most common, with less than 5% of
normal αIIbβ3 levels. Type II has 5-20% of normal levels, and the variant type
has adequate levels but only nonfunctional αIIbβ3. In some cases, the cause of
the disorder is unknown. The diagnostic features of Glanzmann Thrombasthenia
include the absence of platelet aggregation and recurring episodes of
mucocutaneous and spontaneous bleeding. Purpura, epistaxis, and gingival
bleeding are common manifestations, and red blood cell transfusions may be
required in severe cases. The onset of symptoms can occur shortly after birth,
and most patients are diagnosed before age 5. The risk of severe bleeding
decreases with age, but fatal bleeding episodes can occur at any point in the
lifespan of a patient with GT.
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In general population prevalence of glanzmann
thrombasthenia estimated to be 1 per 1,000.
Thelansis’s “Glanzmann Thrombasthenia
(GT) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2021 To 2032" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Glanzmann
Thrombasthenia (GT) treatment modalities options for eight major markets (USA,
Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Glanzmann Thrombasthenia (GT) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Glanzmann Thrombasthenia (GT) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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